How Cholesterol Clogs Your Arteries (Atherosclerosis)

Atherosclerosis explained

Atherosclerosis is a specific form of arteriosclerosis in which an artery wall thickens as a result of invasion and accumulation of white blood cells (WBCs) (foam cell) and proliferation of intimal smooth muscle cell creating a fibrofatty plaque.

The accumulation of the white blood cells is termed “fatty streaks” early on because of the appearance being similar to that of marbled steak. These accumulations contain both living, active WBCs (producing inflammation) and remnants of dead cells, including cholesterol and triglycerides. The remnants eventually include calcium and other crystallized materials within the outermost and oldest plaque. The “fatty streaks” reduce the elasticity of the artery walls. However, they do not affect blood flow for decades because the artery muscular wall enlarges at the locations of plaque.

Atherosclerosis Insightfully Explained

To inform on the Atherosclerosis and its complex biological process is the idea of this video, to give insights for the prevention of the cardiovascular risks of diseases.

Atherosclerosis is a chronic disease that remains asymptomatic for decades. Atherosclerotic lesions, or atherosclerotic plaques, are separated into two broad categories: Stable and unstable (also called vulnerable). The pathobiology of atherosclerotic lesions is very complicated, but generally, stable atherosclerotic plaques, which tend to be asymptomatic, are rich in extracellular matrix and smooth muscle cells.

25 Responses to How Cholesterol Clogs Your Arteries (Atherosclerosis)

  1. julianajuliana says:

    go learn English…it’s not tha hard

  2. BrownnnEyes says:

    good vid. i havent watched all of it yet but should probably mention that LDL stands for low density lipoprotein and HDL stands for high density lipoprotein. most people watching this will have exams and have to know 🙂

  3. mightyelroy says:

    My Biology class really liked this one and wanted me to make a comment

  4. dominicdiazRN says:

    WoW !!! great presentation and explained well tnx

  5. iConnecta says:

    100%

  6. Flippy92 says:

    Outstanding video! Just a few notes: the innermost affected layer of the artery is called the tunica intima (composed of endothelial cells). The hardening of artery walls is caused by the death of smooth muscle cells in the tunica media and the deterioration of elastic fibers (then replaced by scar tissue). This hardening is called *arteriosclerosis.*

  7. berenia7 says:

    thx for the illustration, really i could not get a better understanding when reading articles.this is focused and well designed.

  8. buckwheat40 says:

    no more french fries and burgers for me

  9. hairyfatslobpig says:

    I likes the video up to the point they mentioned remember to take your medicine. According to the New England Journal of medicine, about 50% of heart attack victims have normal cholesterol. Their is no evidence that a blood test showing high cholesterol means it will turn into to plaque. That is primarily your genes. Although many anti statins lower readings, there is no evidence to support they help in plaque prevention. Eating well, omega3’s, vitamin C, low dose aspirin and exercise. Thats it

  10. 007riyazkhan says:

    Excellent video…!!!!

  11. jupiterscastle says:

    What the drug companies like this one don’t want you to know is that most people who actually die from heart attacks had high levels of calcium deposits in the arteries. Its the calcium that makes the plaque harder and easier to break and block your arteries.

    This video obviously only talks about cholesterol because its in their best interest to sell more cholesterol medicine.

    Your body makes cholesterol, its needed, the problem is calcium, if you cut the calcium you cut your death risk

  12. TheZachRogers says:

    for a natural cholesterol solution – CholestProtect—-

  13. tanyabirkiv says:

    thx. i really like this video.

  14. MrAltamashqureshi says:

    loved the video. i made my parents watch it. thnks…

  15. DFresh215 says:

    Decrease LDL, decrease ApoB, increase HDL (exercise).. this video is real info, no need to fight it

  16. arouny145 says:

    this video really helpd for my courswork

  17. misanthroposy says:

    1:53 She says once this layer is damaged. Did she specify why it was damaged? People have been really misled as to how cholesterol actually works. And first off. Cholesterol is cholesterol. Their is no good and bad. LDL means low-density lipo-proteins. no where in that term is cholesterol stated. people get the proteins which only transport the cholesterol mixed up with the actual cholesterol. Look the information up. Their isn’t enough room for me to write how cholesterol really works here.

  18. misanthroposy says:

    @DFresh215 HDL is just a protein that takes the damaged cholesterol back to your liver, where cholesterol is manufactured and then the old cholesterol is recycled and turned back into new cholesterol. Your body isn’t stupid. Eating cholesterol has little if anything to do with cholesterol levels in humans.

  19. airkiro says:

    Amazing Video

  20. BlackGrapes says:

    Thanks for your information! I really checked up on it once i read this comment. Now i know that cholesterol really IS just one type of molecule, but there REALLY are good and bad cholesterol, right? it’s just categorised according to whether it is transported in low-density (bad) or high density lipoproteins, right?

  21. BlackGrapes says:

    Thanks for your information! I really checked up on it once i read this comment. Now i know that cholesterol really IS just one type of molecule, but there REALLY are good and bad cholesterol, right? it’s just categorised according to whether it is transported in low-density (bad) or high density lipoproteins, right?

  22. BlackGrapes says:

    Thanks for your information! I really checked up on it once i read this comment.

  23. BlackGrapes says:

    To:misanthroposy
    Now i know that cholesterol really IS just one type of molecule, but there REALLY are good and bad cholesterol, right? it’s just categorised according to whether it is transported in low-density (bad) or high density lipoproteins, right?

  24. BlackGrapes says:

    Thanks for your information! After reading your comment, i really checked up on it. Now i know that cholesterol really IS just one type of molecule, but there REALLY are good and bad cholesterol, right? it’s just categorised according to whether it is transported in low-density (bad) or high density lipoproteins, right?

  25. BlackGrapes says:

    To:misanthroposy
    Thanks for your information! After reading your comment, i really checked up on it. Now i know that cholesterol really IS just one type of molecule, but there REALLY are good and bad cholesterol, right? it’s just categorised according to whether it is transported in low-density (bad) or high density lipoproteins, right?

Share your suggestion or experience here

error: Share on FB, Twitter, WhatsApp